© Tsukamoto Lab, International Research Center for Infectious Diseases Laboratory of Bacterial Zoonoses, Research Institute for Microbial Diseases(RIMD), Osaka University
- The autotransporter BafA contributes to the proangiogenic potential of Bartonella elizabethae.
Suzuki N, Kumadaki K, Tatematsu K, Doi Y, Tsukamoto K.
Microbiol Immunol (2023) doi: 10.1111/1348-0421.13057. - Comparison of biological activities of BafA family autotransporters within Bartonella Species derived from cats and rodents.
Kumadaki K, Suzuki N, Tatematsu K, Doi Y, Tsukamoto K.
Infect Immun (2023) doi: 10.1128/iai.00186-22. - The passenger domain of Bartonella bacilliformis BafA promotes endothelial cell angiogenesis via the VEGF receptor signaling pathway.
Tsukamoto K, Kumadaki K, Tatematsu K, Suzuki N, Doi Y.
mSphere (2022) doi: 10.1128/msphere.00081-22. - Functional and structural characterization of acquired 16S rRNA methyltransferase NpmB1 conferring pan-aminoglycoside resistance.
Kawai A, Suzuki M, Tsukamoto K, Minato Y, Doi Y.
Antimicrob Agents Chemother (2021) doi: 10.1128/AAC.01009-21. - The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis.
Tsukamoto K, Shinzawa N, Kawai A, Suzuki M, Kidoya H, Takakura N, Yamaguchi H, Kameyama T, Inagaki H, Kurahashi H, Horiguchi Y, Doi Y.
Nat Commun (2020) doi: 10.1038/s41467-020-17391-2. - Bordetella dermonecrotic toxin is a neurotropic virulence factor that uses CaV3.1 as the cell surface receptor.
Teruya S, Hiramatsu Y, Nakamura K, Fukui-Miyazaki A, Tsukamoto K, Shinoda N, Motooka D, Nakamura S, Ishigaki K, Shinzawa N, Nishida T, Sugihara F, Maeda Y, Horiguchi Y.
mBio (2020) doi: 10.1128/mBio.03146-19. - Translocation domain of botulinum neurotoxin A subtype 2 potently induces entry into neuronal cells.
Kohda T, Tsukamoto K, Torii Y, Kozaki S, Mukamoto M.
Microbiol Immunol (2020) doi: 10.1111/1348-0421.12796. - CRISPR/Cas9-mediated genomic deletion of the beta-1, 4 N-acetylgalactosaminyltransferase 1 gene in murine P19 embryonal carcinoma cells results in low sensitivity to botulinum neurotoxin type C.
Tsukamoto K, Ozeki C, Kohda T, Tsuji T.
PLoS One (2015) doi: 10.1371/journal.pone.0132363. - Large-scale preparation of Shiga toxin 2 in Escherichia coli for toxoid vaccine antigen production.
Arimitsu H, Sasaki K, Shimizu T, Tsukamoto K, Tsuji T.
Microbiol Immunol (2013) doi: 10.1111/j.1348-0421.2012.12004.x. - P19 embryonal carcinoma cells exhibit high sensitivity to botulinum type C and D/C mosaic neurotoxins.
Tsukamoto K, Arimitsu H, Ochi S, Nakamura K, Tanaka Y, Nuemket N, Taniguchi K, Kozaki S, Tsuji T.
Microbiol Immunol (2012) doi: 10.1111/j.1348-0421.2012.00490.x. - Unique biological activity of botulinum D/C mosaic neurotoxin in murine species.
Nakamura K, Kohda T, Shibata Y, Tsukamoto K, Arimitsu H, Hayashi M, Mukamoto M, Sasakawa N, Kozaki S.
Infect Immun (2012) doi: 10.1128/IAI.00302-12. - Structural and mutational analyses of the receptor binding domain of botulinum D/C mosaic neurotoxin: Insight into the ganglioside binding mechanism.
Nuemket N, Tanaka Y, Tsukamoto K, Tsuji T, Nakamura K, Kozaki S, Yao M, Tanaka I.
Biochem Biophys Res Commun (2011) doi: 10.1016/j.bbrc.2011.06.173. - Single chain variable fragment antibodies against Shiga toxins isolated from a human antibody phage display library.
Neri P, Shigemori N, Hamada-Tsutsumi S, Tsukamoto K, Arimitsu H, Shimizu T, Akahori Y, Kurosawa Y, Tsuji T.
Vaccine (2011) doi: 10.1016/j.vaccine.2011.05.093. - Preliminary X-ray crystallographic study of the receptor-binding domain of the D/C mosaic neurotoxin from Clostridium botulinum.
Nuemket N, Tanaka Y, Tsukamoto K, Tsuji T, Nakamura K, Kozaki S, Yao M, Tanaka I.
Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) doi: 10.1107/S1744309110012182. - Nucleotide sequence analysis of the enterotoxigenic Escherichia coli Ent plasmid.
Ochi S, Shimizu T, Ohtani K, Ichinose Y, Arimitsu H, Tsukamoto K, Kato M, Tsuji T.
DNA Res (2009) doi: 10.1093/dnares/dsp015. - Lincomycin-induced over-expression of mature recombinant cholera toxin B subunit and the holotoxin in Escherichia coli.
Arimitsu H, Tsukamoto K, Ochi S, Sasaki K, Kato M, Taniguchi K, Oguma K, Tsuji T.
Protein Expr Purif (2009) doi: 10.1016/j.pep.2009.04.011 - Identification of the receptor-binding sites in the carboxyl-terminal half of the heavy chain of botulinum neurotoxin types C and D.
Tsukamoto K, Kozai Y, Ihara H, Kohda T, Mukamoto M, Tsuji T, Kozaki S.
Microb Pathog (2008) doi: 10.1016/j.micpath.2007.12.003. - A nasal vaccine comprising B-subunit derivative of Shiga toxin 2 for cross-protection against Shiga toxin types 1 and 2.
Tsuji T, Shimizu T, Sasaki K, Tsukamoto K, Arimitsu H, Ochi S, Taniguchi K, Noda M, Neri P, Mori H.
Vaccine (2008) doi: 10.1016/j.vaccine.2008.02.034. - Protection of mice from Shiga toxin-2 toxemia by mucosal vaccine of Shiga toxin 2B-His with Escherichia coli enterotoxin.
Tsuji T, Shimizu T, Sasaki K, Shimizu Y, Tsukamoto K, Arimitsu H, Ochi S, Sugiyama S, Taniguchi K, Neri P, Mori H.
Vaccine (2008) doi: 10.1016/j.vaccine.2007.11.038. - Molecular properties of each subcomponent in Clostridium botulinum type B haemagglutinin complex.
Arimitsu H, Sakaguchi Y, Lee J C, Ochi S, Tsukamoto K, Yamamoto Y, Ma S, Tsuji T, Oguma K.
Microb Pathog (2008) doi: 10.1016/j.micpath.2008.04.007. - Protective effect of botulinum C/D mosaic toxoid against avian botulism.
Takeda M, Kasai H, Torii Y, Mukamoto M, Kohda T, Tsukamoto K, Kozaki S.
J Vet Med Sci (2006) doi: 10.1292/jvms.68.325 - Binding of Clostridium botulinum type C and D neurotoxins to ganglioside and phospholipid. Novel insights into the receptor for clostridial neurotoxins.
Tsukamoto K, Kohda T, Mukamoto M, Takeuchi K, Ihara H, Saito M, Kozaki S.
J Biol Chem (2005) doi: 10.1074/jbc.M507596200. - Characterization of the neurotoxin produced by isolates associated with avian botulism.
Takeda M, Tsukamoto K, Kohda T, Matsui M, Mukamoto M, Kozaki S.
Avian Dis (2005) doi: 10.1637/7347-022305R1.1 - Involvement of the C-terminal tail of Arthrobacter ureafaciens sialidase isoenzyme M in cleavage of the internal sialic acid of ganglioside GM1.
Iwamori M, Kaido T, Iwamori Y, Ohta Y, Tsukamoto K, Kozaki S.
J Biochem (Tokyo) (2005) doi: 10.1093/jb/mvi126 - Sequence of the gene for Clostridium botulinum type B neurotoxin associated with infant botulism, expression of the C-terminal half of heavy chain and its binding activity.
Ihara H, Kohda T, Morimoto F, Tsukamoto K, Karasawa T, Nakamura S, Mukamoto M, Kozaki S.
Biochim Biophys Acta (2003) doi: 10.1016/s0167-4781(02)00537-7 - Characterization of Clostridium butyricum neurotoxin associated with food-borne botulism.
Tsukamoto K, Mukamoto M, Kohda T, Ihara H, Wang X, Maegawa T, Nakamura S, Karasawa T, Kozaki S.
Microb Pathog (2002) doi: 10.1006/mpat.2002.0525 - Genetic analysis of type E botulinum toxin-producing Clostridium butyricum strains.
Wang X, Maegawa T, Karasawa T, Kozaki S, Tsukamoto K, Gyobu Y, Yamakawa K, Oguma K, Sakaguchi Y, Nakamura S.
Appl Environ Microbiol (2000) doi: 10.1128/AEM.66.11.4992-4997.2000